Characterization and Antibacterial Activity of Electrospun Polyethylene oxide/Chitosan Nanofibers

This study aims to characterize and evaluate polyethylene oxide (PEO) chitosan (CS) nanofibers produced by electrospinning method. Electrospinning solutions were used at three different concentrations (1, 2, 3 wt%) with five PEO/CS mixing ratios (30/70, 40/60, 50/50, 60/40, 100/0). FESEM, XRD FTIR tests applied for characterization of the nanofibers. Antibacterial activity against Staphylococcus aureus Klebsiella pneumoniae microorganisms was investigated using disk diffusion While 1 wt% concentration not suitable obtain regular nanofibers, uniform largely free beads other ones (2, wt%). The average diameters varied from 59 298 nm depending on ratio. Strong hydrogen bonds formed between two polymers, while crystal structure PEO did change significantly when mixed chitosan. showed no resistance selected bacteria.